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SUPREP Preparation

SUPREP Preparation for Colonoscopy

In order to achieve an accurate evaluation of your lower gastrointestinal (GI) tract, it is important that you properly prepare for the procedure. Doctors are able to obtain the clearest view of the bowel when it is flushed completely free of waste material. The thoroughness of this intestinal cleaning depends on you. Without your cooperation, the examination cannot accomplish its purpose and may have to be repeated.

If you are taking anticoagulants or blood thinners such as, but not limited to, Coumadin (warfarin), Plavix (clopidogrel), Persantine, Aggrenox, Effient, Pradaxa, Xarelto or Eliquis, please discuss this with your Health Care Provider. In most circumstances, these medications are temporarily discontinued prior to your procedure. This bowel preparation should not be used if you have a history of congestive heart failure, renal failure or renal impairment.

If you have questions or you need to reschedule or cancel your procedure, please call (717) 761-0930.


  1. SUPREP Bowel Prep Kit – Prescription sent to your local pharmacy.

5 Days Before Procedure

  1. Do not take any ibuprofen products (nonsteroidal anti-inflammatories – NSAIDS). Tylenol (acetaminophen) is allowed. If you are on aspirin you may continue the aspirin.
  2. Do not take oral iron tablets.
  3. Do not consume any foods that contain seeds or nuts. These foods take longer to pass through the bowel and should be avoided.

The Day Before Procedure

  1. You will need to follow a clear liquid diet the entire day before your procedure. We ask that you avoid dark colored clear liquids (red, purple, or dark blue). NO milk products, NO vegetables, NO breads or grains, NO meats and NO fats or oils are allowed. By rule of thumb, a clear liquid is one that can be seen through. Some examples include clear juices without pulp, clear soda, chicken or beef broth, popsicles, Jell-O, Italian ice, tea, coffee, clear hard candy, etc. If you are diabetic, drink regular (non-diet) liquids in moderation throughout the day.
  2. At 5:00 p.m., pour one 6-ounce bottle of SUPREP into the mixing container. Add cool drinking water to the 16-ounce line on the container and mix. Drink ALL the liquid in the container within 20 minutes. You must drink two (2) more 16-ounce containers of water over the next 1 hour. After the second glass of water you may continue to drink clear liquids.

Second Dose of Preparation

  1. At _________ (6 hours before your scheduled procedure), pour one 6 ounce bottle of SUPREP liquid into the mixing container. Add cool drinking water to the 16 ounce line on the container and mix. Drink ALL the liquid in the container. You must drink two (2) more 16 ounce containers of water over the next 1 hour. You must have completed the prep 4 hours prior to your procedure time. NOTE: If you are scheduled for an early morning procedure, you will need to set your alarm to assure the preparation is taken at the correct time. We are aware of the inconvenience but the two-stage prep provides a superior cleansing of the colon.

On the Day of the Procedure

  1. Do not have anything to eat.
  2. At 6:00 a.m., take any currently prescribed heart and blood pressure medications with a sip of water.
  3. If you are diabetic: Do not take your diabetic medications (pills or insulin) the morning of your procedure. If you normally monitor your blood sugars at home, please check your blood sugar the morning of your procedure. If your blood sugar is over 150 or below 90, please contact the West Shore Endoscopy Center at (717) 975-2430. An anesthesia specialist will provide you with further instructions.
  4. Stop drinking clear liquids at __________, 4 hours before the procedure. No chewing gum, hard candy, or chewing tobacco within 4 hours of your procedure.
  5. Please report to your appointment at the scheduled time. NOTE: Plan to be at the procedure center for about two to two and one-half hours.
  6. A driver must come with you in order to drive you home after the procedure. You will be sedated for your colonoscopy. You may not drive or work for 12 hours after the procedure. For later afternoon procedures, drivers must be no later than 4:00 p.m. The West Shore Endoscopy Center closes at 4:00 p.m.
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