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ciprofloxacin (sip roh FLOX
a sin)
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Cipro
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100 mg
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250 mg
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500 mg
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750 mg
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Cipro is also available as a Liquid.
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This drug is not available in a generic form.
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What is ciprofloxacin?
This drug is an antibiotic which kills bacteria and
clears up infection within the body.
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What is it used for?
In gastroenterology the drug may be very helpful in
controlling the bacterial infection that often is present in
Crohn's disease. It is also used to treat many other forms
of infection in the body.
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How do I take it?
Follow your physician's instructions carefully.
Ciprofloxacin may be taken with or without meals. The best
time to take it is 2 hours after a meal. Drink plenty of
fluids while taking this medication. Antibiotics work best
when taken at the same time each day. Tablets may be crushed
and sprinkled in soft food. Keep liquid cold or at room
temperature-below 86°. Shake well before using. It is
very important to avoid antacids for 2 hours before or after
taking ciprofloxacin. Keep all medications away from
children. Never share your medications with anyone else.
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What do I do for a missed dose?
Ciprofloxacin, like other antibiotics, works best when
there is a steady blood level. Therefore, try not to miss
any doses and take them at evenly spaced intervals. If you
do miss a dose, take it as soon as you remember. If it is
almost time for your next dose, skip the one you missed and
go back to your regular schedule. Do not take 2 doses at the
same time.
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Are there interactions with food or beverages?
This drug may increase the effects of caffeine. Caffeine
is found in many foods and beverages including coffee, tea,
chocolate and soda.
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Are there interactions with other drugs?
An interaction generally means that one drug may increase
or decrease the effect of another drug. Also, the more
medications a person takes, the more likely there will be a
drug interaction.
Interactions with this drug may occur with the following:
- theophylline (Theo-Dur)
- cyclosporine (Sandimmune, Neoral)
- phenytoin (Dilantin)
- blood thinners (Coumadin)
- probenecid
- sucralfate (Carafate)
- glyburide (Diabeta, Micronase, Glynase)
- cimetidine (Tagamet)
- all antacids
- iron medicines
- multi-vitamins containing zinc
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Is there a problem if I have another disorder or
disease?
At times, a drug may have a different or enhanced effect
when other diseases are present. At other times, the drug
may worsen or effect another disease. Patients who have
severe chronic kidney disease or who are on dialysis may
need dosage adjustment. In addition, those patients who have
had convulsions, seizures or a previous stroke should
discuss its use with the physician.
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What about allergies?
People who have known allergies or asthma may be at an
increased risk for a reaction from any new medication. The
physician should always know a patient's allergy history.
Signs of an allergic reaction are skin rash, hives and
swelling. Of course, a person should not take ciprofloxacin
if there has been a previous reaction to this or a similar
drug.
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What if I'm pregnant, considering pregnancy or
breast-feeding?
Most females now know that, if possible, no drug,
including alcohol, should be taken during pregnancy or
lactation. The potential danger, of course, is an injury to
the baby. However, some drugs are much safer than others in
this regard. So, the FDA has a grading system for each drug
which reflects what is known medically. It ranks drugs from
A, where medical studies show no evidence for danger to the
fetus or mother, to B, C, D and X, where the medical
evidence indicates that the risk to the fetus outweighs any
benefit to the mother. Ciprofloxacin is ranked C. Always
consult your physician before taking any drug during or when
planning pregnancy.
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What are the effects on sexual function?
There are no known effects of ciprofloxacin on sexual
function.
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Are there other precautions?
- Ciprofloxacin should not be used in infants or in
children up to 18 years of age.
- With prolonged use, crystals may form in the kidney.
This may be prevented by maintaining a generous urine
flow by drinking several quarts of liquid each day.
- Continued or prolonged use of this as well as other
antibiotics may result in a fungal infection. These
usually occur in the mouth, rectum or vagina.
- People taking ciprofloxacin may suffer torn tendons.
The achilles tendon just above the heel on the back of
the leg is a common site. If you feel any pain or
inflammation in a tendon area, stop taking the
medication, avoid exercise and contact your
physician.
- Ciprofloxacin may rarely cause photosensitivity.
Limit your exposure to the sun or ultraviolet lights
until this effect is known. Notify your physician if you
experience a sunburn-like reaction.
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How long is it safe to take ciprofloxacin?
This drug usually can be taken long-term. The length of
treatment depends upon the severity of the infection.
Generally, ciprofloxacin should be continued for at least 2
days after symptoms have disappeared.
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How about side effects?
Adverse reactions can occur with any drug, even
over-the-counter medications. Some of these are mild such as
a stomach upset, which may be avoided by taking the
medication with food. Minor reactions may go away on their
own but if they persist, contact the physician. For major
reactions, the patient should contact the physician
immediately.
For ciprofloxacin, the following are the observed side
effects:
Minor:
- nausea
- headache
- indigestion
- rash
- constipation
- diarrhea
Major:
- fever
- sore throat
- visual disturbances
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A physician's comment...
Most antibiotics taken by mouth are fairly safe. However,
resistance to these drugs does occur when they are used too
often. Therefore, antibiotics should only be used for
specific purposes and for the length of time decided by the
physician.
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Posted: July 1998
Crohn's
Disease
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